PERTUSSIN

INSTRUCTION FOR MEDICAL USE OF THE MEDICINAL PRODUCT PERTUSSIN (PERTUSSIN)

Composition:

Active substances: 100 g of the medicinal product contains thyme liquid extract (extracti thymi fluidi) (1:1) (extraction solvent – a mixture: 30% (v/v) ethanol and glycerol (48:1)) – 12 g, potassium bromide – 1 g;

Excipients: ethanol 80%, sugar syrup.

Pharmaceutical form. Syrup.

Main physicochemical properties: brown liquid with an aromatic odor. Formation of a slight precipitate may occur upon storage.

Pharmacotherapeutic group. Products used for cough and colds. Expectorants. ATC code R05C A10.

Pharmacological properties.

Pertusin accelerates expectoration of sputum, has a soothing effect and exerts a sedative action. The drug stimulates mucociliary clearance. The presence in the extract of thyme of essential oil, tannins and bitter substances determines the ability to irritate nerve endings (mainly parasympathetic), thereby enhancing secretion of liquid bronchiolar fluid, reducing the viscosity of bronchial secretions. It promotes productive cough, enhances sputum expectoration, increases ciliary epithelium activity, and improves drainage function of the bronchial tree.

Clinical characteristics.

Indications.

Symptomatic treatment of inflammatory respiratory tract diseases accompanied by cough: bronchitis, tracheitis, pneumonia, pertussis.

Contraindications.

Hypersensitivity to the components of the drug (including bromides) or to other plants of the Lamiaceae family, as well as sensitivity to celery and birch pollen (cross-reaction possible); decompensated cardiovascular disorders, arterial hypotension, severe atherosclerosis, anemia, kidney diseases, diabetes mellitus, alcoholism. Children under 4 years of age.

Interaction with other medicinal products and other forms of interaction.

Barbiturates may be incompatible with potassium bromide. Concurrent use of Pertussin and barbiturates requires caution (potentiation of the effect of the latter).

Inform your doctor about the concurrent use of any other medicinal products!

Special precautions for use

If symptoms worsen and/or dyspnea, fever, or purulent sputum occur during treatment with the medicinal product, consult a physician. If symptoms persist after one week of treatment, consult a physician.

Patients with impaired glucose tolerance should consult a physician before using the medicinal product.

Sucrose content in the product: in 1 teaspoon (5 ml) – from 2.92 g to 4.04 g, in 1 dessert spoon (10 ml) – from 5.84 g to 8.08 g, in 1 tablespoon (15 ml) – from 8.76 g to 12.12 g. May be harmful to teeth.

Children aged 4 to 6 years should dilute the product with boiled water.

This medicinal product contains 8–11 vol.% ethanol (alcohol); the content of absolute alcohol is: in 1 teaspoon (5 ml) – from 0.42 g to 0.80 g, in 1 dessert spoon (10 ml) – from 0.84 g to 1.60 g, in 1 tablespoon (15 ml) – from 1.26 g to 2.40 g.

Harmful for patients suffering from alcoholism. Caution is advised when administering to children and patients with liver disorders or epilepsy.

Use during pregnancy or breastfeeding

Due to insufficient data, the use of this medicinal product is not recommended during pregnancy or breastfeeding.

Ability to affect reaction speed when driving or operating machinery

Since the product contains alcohol, patients should exercise caution when driving or operating machinery.

Dosage and Administration.

For oral use. Adults and children aged 12 years and older: 1 tablespoon (15 ml) three times a day.

Children aged 4 to 6 years: ½ teaspoon (2.5 ml) three times a day; children aged 6 to 9 years: 1 teaspoon (5 ml) three times a day; children aged 9 to 12 years: 1 dessert spoon (10 ml) three times a day.

For children under 6 years of age, the single dose of ½ teaspoon (2.5 ml) should be dissolved in 2 dessert spoons (20 ml) of cooled boiled water.

The duration of treatment is determined by the physician depending on the course of the disease, the nature of combination therapy, and the patient's tolerance to the drug.

Children. To be used in children aged 4 years and older under medical prescription.

Overdose.

In case of overdose, adverse effects and allergic reactions may be intensified. Symptomatic therapy is recommended.

Side effects.

With prolonged use, symptoms of bromism are possible: skin rash, rhinitis, conjunctivitis, gastroenterocolitis, general weakness, ataxia, bradycardia. Treatment of bromism involves discontinuation of the drug and enhanced elimination of bromide salts (administration of large amounts of sodium chloride, fluids, diuretic agents).

Allergic reactions to the components of the drug are possible. Gastrointestinal disturbances (including nausea, vomiting, diarrhea) may occur.

If any adverse events occur, consult a physician immediately!

Shelf life. 4 years.

Storage conditions. Store in the original packaging at a temperature not exceeding 25 °C. Keep out of reach of children.

Packaging. 100 g in bottles or jars; 100 g in bottles or jars, one bottle or jar per carton.

Availability. Over-the-counter.

Manufacturer. JSC "Halychpharm".

Manufacturer's address and place of business.

6/8 Opryshkivska Street, Lviv, 79024, Ukraine.