PERTUSSIN

INSTRUCTION FOR MEDICAL USE OF THE MEDICINAL PRODUCT PERTUSIN

Composition:

Active ingredients: 100 g of syrup contains liquid extract of wild thyme (Thymus serpyllum) (1:1) (extraction agent – 80% ethanol) – 12 g, potassium bromide – 1 g;

1 ml of syrup contains liquid extract of wild thyme (Thymus serpyllum) (1:1) (extraction agent – 80% ethanol) – 0.16 g, potassium bromide – 0.01 g;

Excipient: sugar syrup.

The preparation contains 8–11% ethanol; the content of absolute alcohol is: up to 0.43 g in 1 teaspoon (5 ml), up to 0.87 g in 1 dessert spoon (10 ml), up to 1.3 g in 1 tablespoon (15 ml).

The sucrose content in 1 teaspoon (5 ml) of the preparation corresponds to approximately 0.32 bread units, in 1 dessert spoon (10 ml) – approximately 0.64 bread units, in 1 tablespoon (15 ml) – approximately 0.96 bread units.

Pharmaceutical form. Syrup.

Main physicochemical properties: brown liquid with a pleasant odor.

Pharmacotherapeutic group.

Respiratory system. Cough and cold preparations. Expectorants, combinations. ATC code R05C A10.

Pharmacological properties.

Pharmacodynamics.

Pertusin belongs to the group of secretomotor agents. It stimulates the physiological activity of the ciliated epithelium and peristaltic movements of the bronchioles, promoting the movement of mucus from the lower to the upper respiratory tract and its subsequent expulsion. The drug softens cough and exerts a soothing effect.

Clinical Characteristics.

Indications.

Cough associated with bronchitis, tracheitis, pneumonia, whooping cough, and inflammatory diseases of the upper respiratory tract.

Contraindications.

Hypersensitivity to the components of the drug, including bromides or to other plants of the Lamiaceae family; sensitivity to celery and birch pollen (possible cross-reaction); decompensated cardiovascular disease, arterial hypotension, severe atherosclerosis, anemia, renal diseases, diabetes mellitus, alcoholism.

Special precautions.

Patients with impaired glucose tolerance must consult a physician before taking this medication.

The recommended dosage must be strictly observed during treatment.

Interaction with other medicinal products and other forms of interaction.

Concomitant use of potassium bromide is incompatible or requires caution with barbiturates (their effect is potentiated).

Inform your doctor if you are taking any other medicinal products!

Special precautions for use.

If symptoms worsen and/or dyspnea, fever, or purulent sputum occur during treatment with the medicinal product, medical advice must be sought.

If symptoms persist for more than one week, medical advice must be sought. The recommended doses should be strictly followed when using the medicinal product.

This medicinal product contains 8–11 vol.% ethanol (alcohol), i.e. 1.3 g per dose (15 ml), equivalent to 26 ml of beer or 11 ml of wine per dose. It may be harmful for patients suffering from alcoholism.

Use during pregnancy or breastfeeding.

Due to insufficient data, the use of this medicinal product is not recommended during pregnancy or breastfeeding.

Ability to affect reaction speed when driving or operating machinery.

Since the product contains alcohol, patients should exercise caution when driving or operating machinery.

Dosage and Administration.

The medication should be taken orally.
Children aged 4 to 6 years: 2.5–5 ml of the medication (½–1 teaspoon), previously dissolved in 20 ml (2 dessert spoons) of cooled boiled water, 3 times daily.
Children aged 6 to 12 years: 10–15 ml (1 dessert spoon or 1 tablespoon) 3 times daily.
Adults: 15 ml (1 tablespoon) 3 times daily.

The duration of treatment is determined individually by a physician.

Children.
The medication may be used in children aged 4 years and older only as prescribed by a physician.

Overdose.
In case of overdose, adverse effects and allergic reactions may be intensified. Treatment is symptomatic.

Side effects.

With prolonged use, symptoms of bromism are possible: skin rash, rhinitis, conjunctivitis, gastroenterocolitis, general weakness, ataxia, bradycardia. Treatment of bromism consists of discontinuing the drug and enhancing elimination of bromide salts (administration of large amounts of sodium chloride, fluids, and diuretics).

Allergic reactions to the components of the drug are possible. Gastrointestinal disturbances (including nausea, vomiting, diarrhea) may occur.

In case of any adverse events, consult a physician!

Shelf life. 4 years.

Shelf life after opening the bottle – 3 months.

Storage conditions.

Store in the original packaging at a temperature not exceeding 25 °C. Keep out of reach of children.

Do not use the drug after the expiry date stated on the packaging!

Packaging.

100 g in a bottle; 1 bottle per cardboard box; 100 g in bottles; 200 g in bottles with or without nozzle; 1 bottle per cardboard box; 200 g in bottles with or without nozzle.

Prescription status. Over-the-counter.

Manufacturer. JSC "Pharmaceutical Factory "Viola".

Manufacturer's address.

75 Amosova Akademika Street, Zaporizhzhia, Ukraine, 69063.

Marketing Authorization Holder. JSC "Pharmaceutical Factory "Viola".

Address of the Marketing Authorization Holder.

75 Amosova Akademika Street, Zaporizhzhia, Ukraine, 69063.