STIMOL
UkraineThe drug is used for the symptomatic treatment of asthenia (physical, mental, postoperative, post-infectious, or age-related), as well as for hypotonic-type vegetative-vascular dystonia, alcohol withdrawal syndrome, and sexual asthenia. For athletes, it helps relieve muscle pain and cramps caused by physical exertion.
Frequently asked questions
How should Stimol be taken correctly?
The powder should be dissolved in a glass of water (approximately 100 ml) or a sweetened beverage (tea, juice, compote) and taken during meals. For adults, it is recommended to take 1 sachet 3 times a day; for children aged 6 and older, 1 sachet 2 times a day. The recommended course is 4 weeks.
Who should not take this drug?
Contraindications include hypersensitivity to any component of the composition and the presence of gastric or duodenal ulcers. It is also not recommended to use the drug during pregnancy and breastfeeding, as safety during these periods has not been established.
What side effects can Stimol cause?
In rare cases, gastralgia or a burning sensation in the stomach may occur at the beginning of treatment. If any adverse reactions occur, you should discontinue use and consult a physician.
Can people with diabetes mellitus take this drug?
Yes, since the composition does not contain sugar, the drug can be used by people with diabetes mellitus.
Should dietary restrictions be taken into account when taking it?
Yes, one sachet contains approximately 100 mg of sodium, which should be taken into account by individuals on a salt-free diet.
Instructions for use
INSTRUCTION FOR MEDICAL USE OF THE MEDICINAL PRODUCT STIMOL® (STIMOL®)
Composition:
Active substance: citrulline malate;
1 sachet contains 1 g of citrulline malate (equivalent to 566.44 mg of L-citrulline and 433.56 mg
of DL-malic acid (E 296));
Excipients: povidone, sodium hydrogencarbonate, maltodextrin, sodium saccharin, strawberry flavor.
Pharmaceutical form. Effervescent powder for oral solution.
Main physicochemical properties: white powder with a strawberry odor.
Pharmacotherapeutic group. Agents affecting the digestive system and metabolic processes. Amino acids and their derivatives. ATC code A16A.
Pharmacological properties.
Pharmacodynamics.
Citrulline malate is an equimolar mixture of malic acid and citrulline.
Malic acid stimulates the Krebs cycle and activates energy production mechanisms at the cellular level. Citrulline is involved in the urea cycle and promotes the formation and excretion of urea from the body.
Pharmacokinetics.
Citrulline malate is rapidly absorbed in the intestine. Maximum concentration is reached within 45 minutes, exceeding the baseline concentration by 6–15 times, and returns to baseline levels within 5–6 hours. The drug is excreted in urine after rapid elimination from plasma.
Clinical characteristics.
Indications.
Symptomatic treatment of asthenia:
− physical asthenia;
− psychic asthenia;
− post-infectious asthenia;
− postoperative asthenia;
− asthenia in elderly patients;
− asthenia in athletes (the drug relieves muscle pain and cramps caused by lactate accumulation after physical exertion and intensive training);
− vegetative-vascular dystonia of hypotensive type;
− alcohol withdrawal syndrome;
− sexual asthenia.
Contraindications.
Hypersensitivity to any component of the drug. Gastric or duodenal ulcer.
Interaction with other medicinal products and other forms of interaction.
Unknown.
Instructions for use.
One sachet of Stimol**®** contains approximately 100 mg of sodium. This should be taken into account when administering the drug to patients on a salt-free diet.
Since Stimol**®** does not contain sugar, it can be used by patients with diabetes mellitus.
As the powder contained in the sachet is an acidic substance, it should be dissolved in a glass of water or sweetened beverage and taken during meals.
Use during pregnancy or breastfeeding.
Safety of use has not been established; therefore, the use of the drug during these periods is not recommended.
Ability to influence reaction rate when driving or operating machinery.
No effect.
Method of administration and dosage.
Oral administration. Dissolve the contents of the sachet in a glass of water (approximately 100 mL) or a sweetened beverage (tea, juice, fruit drink, etc.) before use. Take during meals.
Adults: 1 sachet 3 times daily.
Children aged 6 years and older: 1 sachet 2 times daily.
Recommended duration of treatment: 4 weeks.
Children. The drug may be used in children aged 6 years and older.
Overdose. Not described.
Adverse reactions.
In rare cases – gastric pain or a burning sensation in the stomach at the beginning of treatment.
If any adverse reactions occur, treatment must be discontinued and medical advice sought.
Shelf life. 3 years.
Storage conditions. Store at a temperature not exceeding 25 °C. Keep out of reach of children.
Packaging. Powder, 1 g per sachet. 18 sachets in a cardboard box.
Availability category. Over-the-counter.
Manufacturer.
BIOCODEX.
Manufacturer’s location and address of place of business.
Manufacturing address: 1 Avenue Blaise Pascal, 60000 Beauvais, France.
I N S T R U C T I O N
for medical use of the medicinal product
STIMOL®
(STIMOL®)
Composition:
Active substance: citrulline malate;
1 sachet contains 1 g of citrulline malate (equivalent to 566.44 mg of L-citrulline and 433.56 mg of DL-malic acid (E 296));
Excipients: povidone, sodium bicarbonate, maltodextrin, sodium saccharin, strawberry flavoring.
Pharmaceutical form. Effervescent powder for oral solution.
Main physicochemical properties: white powder with a strawberry odor.
Pharmacotherapeutic group. Drugs affecting the digestive system and metabolic processes. Amino acids and their derivatives. ATC code: A16A.
Pharmacological properties.
Pharmacodynamics.
Citrulline malate is an equimolar mixture of malic acid and citrulline.
Malic acid stimulates the Krebs cycle and activates cellular energy production mechanisms. Citrulline is involved in the urea cycle and enhances the formation and excretion of urea from the body.
Pharmacokinetics.
Citrulline malate is rapidly absorbed in the intestine. Maximum plasma concentration is reached within 45 minutes, exceeding baseline levels by 6–15 times, and returns to baseline within 5–6 hours. The drug is excreted in urine after rapid elimination from plasma.
Clinical characteristics.
Indications.
Symptomatic treatment of asthenia:
− physical asthenia;
− psychic asthenia;
− post-infectious asthenia;
− postoperative asthenia;
− asthenia in the elderly;
− asthenia in athletes (the drug relieves muscle pain and cramps caused by lactate accumulation following physical exertion and intensive training);
− vegetative-vascular dystonia of the hypotensive type;
− alcohol withdrawal syndrome;
− sexual asthenia.
Contraindications.
Hypersensitivity to any component of the drug. Gastric or duodenal ulcer.
Interaction with other medicinal products and other types of interactions.
Not established.
Special precautions.
One sachet of STIMOL® contains approximately 100 mg of sodium. This should be taken into account when administering the drug to patients on a salt-free diet.
Since STIMOL® contains no sugar, it may be used by patients with diabetes mellitus.
As the powder in the sachet is acidic, it should be dissolved in a glass of water or sweetened beverage and taken during meals.
Use during pregnancy or breastfeeding.
Safety during pregnancy or breastfeeding has not been established; therefore, use during these periods is not recommended.
Effect on ability to drive or operate machinery.
No effect.
Dosage and administration.
For oral use. Dissolve the contents of one sachet in a glass of water (approximately 100 mL) or a sweetened beverage (tea, juice, compote, etc.) and take during meals.
Adults: 1 sachet three times daily.
Children over 6 years: 1 sachet twice daily.
Recommended duration of treatment: 4 weeks.
Children. The drug is indicated for children over 6 years of age.
Overdose. Not reported.
Adverse reactions.
In rare cases – gastric pain or a burning sensation in the stomach at the beginning of treatment.
If any adverse reactions occur, treatment must be discontinued and medical advice sought.
Shelf life. 3 years.
Storage conditions. Store at a temperature not exceeding 25 °C. Keep out of reach of children.
Packaging. Powder, 1 g per sachet. 18 sachets in a cardboard box.
Availability category. Over-the-counter.
Manufacturer.
BIOCODEX.
Manufacturer’s location and address of place of business.
Manufacturing address: 1 Avenue Blaise Pascal, 60000 Beauvais, France.
The original data is available in the language of the country of manufacture.
Data source: State Register of Medicinal Products of Ukraine
Data last verified: August 13, 2026