SODIUM CHLORIDE

INSTRUCTION FOR MEDICAL USE OF THE MEDICINAL PRODUCT Sodium chloride (Sodium chloride)

Composition:

Active substance: sodium chloride;

1 ml of solution contains sodium chloride 9.0 mg;

Excipient: water for injections.

Pharmaceutical form. Solution for injection.

Basic physicochemical properties: clear, colorless liquid.

Pharmacotherapeutic group.

Plasma substitutes and perfusion solutions. Electrolyte solutions. ATC code B05XA03.

Pharmacological properties.

Pharmacodynamics.

0.9% sodium chloride solution normalizes water-electrolyte balance and eliminates fluid deficiency in the human body, which develops during dehydration or due to accumulation of extracellular fluid in large burn and trauma areas, during abdominal surgeries, and peritonitis. The drug improves tissue perfusion and enhances the effectiveness of blood transfusion measures in massive blood loss and severe forms of shock. It also exerts a detoxifying effect due to a transient increase in fluid volume, reduction of toxic substances concentration in blood, and stimulation of diuresis.

Pharmacokinetics.

Rapidly leaves the vascular system. The drug remains in the vascular bed for a short period, after which it passes into the interstitial and intracellular compartments. After 1 hour, only about half of the infused solution remains within blood vessels. Salts and fluid are very rapidly excreted by the kidneys, increasing diuresis.

Clinical characteristics.

Indications.

Preparation of solutions of medicinal products for topical and parenteral administration. Can be used locally for wound irrigation and nasal mucosa.

Contraindications.

Incompatibility of the main medicinal product and the solvent. Do not use the preparation for eye irrigation during ophthalmological surgeries.

Interaction with other medicinal products and other types of interactions.

The preparation is compatible with most medicinal products; therefore, it can be used for dissolving various medicinal products, except those incompatible with sodium chloride as a solvent.

Special precautions for use.

Before dissolving the medicinal product, it is necessary to check whether the use of sodium chloride solution is suitable for dissolving this medicinal product.

Use during pregnancy or breastfeeding.

The drug can be used during pregnancy or breastfeeding.

Ability to influence reaction rate when driving or operating machinery.

No effect.

Method of administration and dosage.

Administer intravenously, intramuscularly, rectally, or subcutaneously (depending on the recommended route of administration).

For wound and mucous membrane irrigation, use sufficient amount of the solution.

Children.

The drug may be administered to children.

Overdose.

Unlikely when used as directed.

Adverse reactions.

Not observed when the drug is used correctly.

Shelf life. 2 years.

Storage conditions.

Store in a place inaccessible to children, at a temperature not exceeding 25 °C. Store in the original packaging.

Incompatibility.

Determined by the medicinal product which should be diluted with sodium chloride solution.

Packaging.

2 ml in single-dose containers, 10 containers per pack; 5 ml in ampoules, 5 ampoules in a blister pack, 1 or 2 blister packs per pack.

Prescription status.

By prescription only.

Manufacturer.

TOB "Yuria-Farm".

Manufacturer's address and location of business activity.

108, Kozbirska St., Cherkasy, Cherkasy region, 18030, Ukraine. Tel.: (044) 281-01-01.