BORIC ACID

INSTRUCTIONS FOR MEDICAL USE OF THE MEDICINAL PRODUCT BORIC ACID (BORIC ACID)

Composition:

Active ingredient: boric acid;

100 ml of solution contain 3 g of boric acid;

Excipients: ethanol 96%, purified water.

Pharmaceutical form.

3% alcoholic solution for external use.

Main physicochemical properties: clear, colorless liquid.

Pharmacotherapeutic group.

Antiseptics and disinfectants.

ATC code: D08AD.

Pharmacological properties.

Pharmacodynamics. The drug exerts an antiseptic effect. It coagulates proteins (including enzymes) of microbial cells, disrupts the permeability of the cell membrane, thereby inhibiting the growth and development of bacteria.

Pharmacokinetics. When applied externally, the drug is absorbed through damaged skin and wound surfaces; if accidentally ingested, it is absorbed through the mucous membrane of the gastrointestinal tract. Boric acid can accumulate in body tissues. It is slowly eliminated from the body.

Clinical characteristics.

Indications.

Pyoderma, weeping eczema, intertrigo, acute and chronic otitis media.

Contraindications.

• Hypersensitivity to boric acid;
• renal function impairment;
• chronic mesotympanitis with normal or slightly altered mucosa;
• traumatic perforations of the tympanic membrane;
• pregnancy and breastfeeding period, including treatment of mammary glands;
• children (including newborns).

Special precautions.

Do not apply the drug to large areas of skin; do not use for cavity irrigation. Avoid contact of the drug with eyes.

The recommended application guidelines must not be violated, as this may harm health.

Interaction with other medicinal products and other forms of interaction.

Interaction is currently unknown.

When using any other medicinal products concurrently, inform the physician.

Usage characteristics.

Use during pregnancy or breastfeeding.

The drug is contraindicated in women during pregnancy or breastfeeding.

Ability to affect reaction speed when driving or operating machinery.

Has no effect.

Method of Administration and Dosage

Apply externally. In cases of pyoderma, diaper rash, and eczema, affected skin areas should be treated with a wipe moistened with the preparation 2–3 times daily.

For otitis, cotton swabs moistened with the solution should be inserted into the external auditory canal, or 3–5 drops should be instilled 2–3 times daily.

Children

The drug is not administered to children.

Overdose

In case of accidental ingestion, perform gastric lavage via a tube, administer saline laxatives and enterosorbents (activated charcoal) orally, as well as symptomatic therapy.

Symptoms of acute poisoning: nausea, vomiting, diarrhea, circulatory disturbances, central nervous system (CNS) depression, decreased body temperature, shock, coma, and erythematous rash. In cases of severe poisoning, measures should be taken to maintain vital functions; hemodialysis or peritoneal dialysis, and blood transfusions may be required. With prolonged use of the drug on large skin areas, symptoms of chronic intoxication may develop: tissue edema, exhaustion, stomatitis, eczema, menstrual cycle disturbances in women, anemia, seizures, and alopecia. In such cases, discontinue the drug and administer symptomatic treatment.

Side effects.

The use of the drug may cause allergic reactions (skin redness, itching, urticaria, rashes, swelling). In isolated cases – development of anaphylactic reactions, including shock; epithelial desquamation.

With prolonged use and in patients with impaired renal function, nausea, vomiting, diarrhea, headache, confusion, oliguria, and seizures may occur.

If any adverse events occur, consult a physician immediately!

Shelf life.

3 years.

The drug must not be used after the expiry date stated on the packaging.

Storage conditions.

Store at a temperature not exceeding 25°C. Keep out of reach of children.

Packaging. 25 ml in a vial. 1 vial per pack.

Availability. Over-the-counter.

Manufacturer: JSC "Farmak".

Manufacturer's address and place of business.

74, Kyrylivska Street, Kyiv, 04080, Ukraine.