CRUSHINI CORTEX

INSTRUCTIONS FOR MEDICAL USE OF THE MEDICINAL PRODUCT BUCKTHORN BARK (FRANGULAECORTEX)

Composition:

Active substance: buckthorn bark (Frangulae cortex);

1 package contains buckthorn bark (Frangulae cortex) – 50 g or 100 g;
1 filter bag contains buckthorn bark (Frangulae cortex) – 1.5 g.

Dosage form. Bark.

Main physico-chemical properties:

ground raw material: fragments of bark of various shapes passing through a sieve with 7 mm diameter openings. The outer surface color is dark brown, grayish-brown, dark gray or gray; the inner surface is yellowish-orange or reddish-brown;

coarse powder: yellowish-brown powder passing through a sieve with 2 mm openings.

For all types of raw material, the odor is weak, the taste is bitter.

Pharmacotherapeutic group.
Laxatives. ATC code A06AB07.

Pharmacological properties.

Pharmacodynamics.

The biologically active substances of the drug exert a mild laxative effect, the mechanism of which is based on enhanced colonic peristalsis, without irritating the mucous membrane and without affecting the small intestine. The laxative effect occurs within 8–12 hours after administration.

Pharmacokinetics.

Pharmacokinetics has not been determined.

Clinical characteristics.

Indications.

Intestinal atony, common constipation.

Contraindications.

Hypersensitivity to the components of the drug. Neurogenic and endocrine constipation, spastic constipation, intestinal obstruction, hemorrhage, acute abdomen syndrome, appendicitis, acute gastroenterocolitis, other inflammatory processes in the abdominal cavity, acute severe conditions.

Special precautions.

Prolonged use of the drug leads to habituation and weakening or absence of laxative effect. To prevent habituation, it is advisable to alternate with other laxatives.

Interaction with other medicinal products and other types of interactions. Unknown.

Special precautions for use.

Use during pregnancy or breastfeeding. Contraindicated.

Ability to affect reaction speed when driving or operating machinery. Does not affect.

Method of Administration and Dosage

Place 1 tablespoon of the bark into an enameled container, pour 200 ml of hot boiled water, cover with a lid, and steep in a water bath at boiling temperature for 30 minutes. Allow to cool at room temperature for 10 minutes, then strain and squeeze the residue into the strained decoction. Adjust the volume of the decoction to 200 ml with boiled water. Administer warm: adults – ½ cup at bedtime; children aged 12 years and older – ¼–⅓ cup at bedtime. Shake the decoction before use.

Place 2 filter bags into a glass or enameled container, pour 100 ml of boiling water, cover, and steep for 15–20 minutes. Administer warm: adults – up to 100 ml at bedtime; children aged 12 years and older – ¼–⅓ cup (50–60 ml) at bedtime.

The duration of treatment is determined individually by a physician.

Children

The use of the drug is recommended for children aged 12 years and older.

Overdose

In case of overdose, colicky abdominal pain, tenesmus, and discomfort may occur. If these symptoms appear, discontinue use of the drug.

Treatment is symptomatic.

Side effects.

With prolonged use, diarrhea with metabolic disturbances, dehydration, reduced intestinal enzyme function, atony of the large intestine, colicky pain, and allergic reactions may develop.

Shelf life. 5 years.

Do not use the medicinal product after the expiry date stated on the packaging.

Storage conditions.

Store in the original packaging at a temperature not exceeding 25 °C, in a place inaccessible to children. Prepared decoction (infusion) should be stored in a cool place (8–15 °C) for no more than 2 days.

Packaging.

50 g or 100 g in packets, inserted into a carton; 1.5 g in filter bags, with 20 filter bags packed into cartons.

Availability classification. Over-the-counter.

Manufacturer. JSC "Pharmaceutical Factory "Viola".

Manufacturer's address and place of business.

69050, Ukraine, Zaporizhzhia, Skladska St., 4.

Marketing authorization holder. JSC "Pharmaceutical Factory "Viola".

Address of the marketing authorization holder.

69063, Ukraine, Zaporizhzhia, Amosova Akademika St., 75.